Myoclonic jerks may also occur these are mild and with no particular circadian distribution. Juvenile absence epilepsy is a genetically determined generalized epilepsy characterized by (a) typical absence seizures occurring frequently with significant impairment of consciousness and (b) generalized tonic-clonic seizures.In this article, the author details clinical, electroencephalographic, genetic, and management aspects of juvenile absence epilepsy and emphasizes how its differential diagnosis compares with other focal and generalized epileptic syndromes. Other antiseizure medications, such as carbamazepine, eslicarbazepine, lacosamide, oxcarbazepine, phenytoin, tiagabine, and vigabatrin, are contraindicated. Appropriate antiseizure treatments include sodium valproate, ethosuximide, lamotrigine, and possibly levetiracetam. Response to appropriate pharmacological treatment is usually excellent, but relapses are common with drug withdrawal. EEG shows classical generalized 3 Hz spike-and-slow-wave discharges. The majority of patients have generalized tonic-clonic seizures, and a few also have sporadic myoclonic jerks. It manifests with severe and frequent absence seizures. Juvenile absence epilepsy is a genetically determined generalized epilepsy syndrome with a peak onset at 9 to 13 years of age.
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